International Journal of Clinical Oncology & Cancer Therapy

Incorporating off-the-shelf reconstruction plates into the digital plan for mandible reconstruction

Kai Cheng, David Leinkram, Dale Howes, Jonathan R. Clark

Digital planning for maxillary and mandibular reconstruction is becoming routine in institutions performing large volumes of microvascular reconstruction.1 Many centres are developing in-house capabilities to contain costs and minimise delays for oncology cases.2-5 Reliable implant-retained dental rehabilitation following mandibulectomy or maxillectomy depends on optimal bone placement, which is difficult to achieve without pre-operative planning, either analogue, based on physical models, or digital, using virtual planning. Dental rehabilitation requires a coordinated plan prior to surgery involving the ablative surgeon, reconstructive surgeon, prosthodontist and design engineers, who perform the digital planning. We have previously described our early experience with in-house virtual surgical planning.2 However; several challenges remained when compared to patient-specific plates, principally because we are unable to 3D print or Computer Numerical Control (CNC) mill a titanium plate for bone fixation. The purpose of this paper is to describe a novel solution that allows the incorporation of non-custom or ‘off -the -shelf” plates into the digital plan for mandibular reconstruction with a free fibula flap using 3D printing and optical scanning.

Network pharmacology to unveil the biological basis of gy ii in breast cancer treatment

Cun-Fang Dai, Hai-Miao Zou, Ting-Ting Ma, Bo-Ran Zhang, Xing Chen, Gan-Lin Zhang, Xiao-Min Wang

The breast cancer is a prevalent case that is recurrent and long-distance metastasis. It is one of the most serious threatening diseases for women all over the world and usually leads to decreased qualities of life. China has a long history of using traditional Chinese medicine (TCM) for treating breast cancer. With increasing scientific evidence in medical research and clinical trials, the use of TCM in cancer treatment is gradually being recognized as a complementary and alternative therapy all over the world.1-3 GY II is a representative type of TCM widely used for breast cancer treatment in China for several decades in Beijing Hospital of Traditional Chinese Medicine. A large amount of medication experience and clinical cases have proved the effectiveness of GY II, which can improve patients' 5-year survival rate and quality of life.

How has Covid-19 Impacted Cancer Research?

Suryakiran Navath

In The onset of Covid-19 has disrupted every aspect of our lives. Unfortunately, those who were already suffering from cancer now have to deal with a new threat. Depending on the severity of their condition, some cancer patients are especially vulnerable to the virus. 

CellSonic Case Reports

Andrew Hagu

There are CellSonic treatments taking place every minute of every day all around the world. We all want to know more, especially those of us making the machines. Unfortunately, we never get enough feedback for two reasons. First of all the machines are bought by customers who are running their clinics as a business and to write reports to us is an unpaid chore. Performing cures has become routine and what at first were seen as miracles has become normal. Secondly, most countries are corrupted by Big Pharma and have laws and regulations requiring only pharmaceuticals to be used in medicine with total ignorance of biophysics and the electrical properties of body cells that are controlled by the mind. CellSonic clinics are praised by their customer patients and feel threatened by regulators who are an ignorant bunch not interested in helping fellow humans.